This review is part of the Collaborative Research Center (CRC) ELAINE 1270 and was prepared under the direction of Hermann Seitz (University of Rostock) in collaboration with international experts. It provides valuable insights into the design and application of hydrogels for the effective repair and regeneration of articular cartilage.
Hydrogels, three-dimensional networks of hydrophilic polymers, offer an innovative basis for tissue regeneration due to their biocompatible and mechanically adaptable properties. The work sheds light on how hydrogels can be designed through targeted material selection, mechanical properties and structuring in such a way that they mimic natural articular cartilage as closely as possible and promote interaction with the surrounding tissue.
With an increasing amount of cartilage damage caused by ageing or injury, often leading to degenerative conditions such as osteoarthritis, the importance of such developments to medical practice and patient wellbeing becomes clear. The advances described in the publication offer potentially important solutions to improve quality of life.
This research highlights the role of innovative biomaterials in modern medical technology and emphasizes the importance of international collaborations in this field.
Further information and access to the publication can be found at https://doi.org/10.1016/j.bioactmat.2024.09.005
Innovative advances in hydrogel design for the regeneration of articular cartilage
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